Phosphorylation of GSK3 α/β correlates with activation of AKT and is prognostic for poor overall survival in acute myeloid leukemia patients

Conclusions These findings suggest that AKT-mediated phosphorylation of GSK3α/β may be beneficial to AML cell survival, and hence detrimental to the overall survival of AML patients. Intrinsically, p-GSK3α/β may serve as an important adverse prognostic factor for a subset of AML patients.
Source: BBA Clinical - Category: Biochemistry Source Type: research