No Evidence for the Benefit of Gonadotropin-Releasing Hormone Agonist in Preserving Ovarian Function and Fertility in Lymphoma Survivors Treated With Chemotherapy: Final Long-Term Report of a Prospective Randomized Trial [Rapid Communication]

Conclusion
To the best of our knowledge, this is the first long-term analysis confirming that GnRHa is not efficient in preventing chemotherapy-induced POF in young patients with lymphoma and did not influence future pregnancy rate. These results reopen the debate about the drug’s benefit in that it should not be recommended as standard for fertility preservation in patients with lymphoma.

Source: Journal of Clinical Oncology - July 19, 2016 Category: Cancer & Oncology Authors: Demeestere, Brice, Peccatori, Kentos, Dupuis, Zachee, Casasnovas, Van Den Neste, Dechene, De Maertelaer, Bron, Englert Tags: Quality of Life, Menopausal Symptoms, Rapid Communications Source Type: research