Downregulation of Cdh1 signalling in spinal dorsal horn contributes to the maintenance of mechanical allodynia after nerve injury in rats

Conclusions This study indicates that a downregulation of Cdh1 expression in spinal dorsal horn is involved in molecular mechanisms underlying the maintenance of neuropathic pain. Upregulation of spinal Cdh1 may be a promising approach to treat neuropathic pain.

http://mpx.sagepub.com/cgi/content/abstract/12/0/1744806916647376?rss=1

Source: Molecular Pain - May 15, 2016 Category: Molecular Biology Authors: Hu, R., Li, L., Li, D., Tan, W., Wan, L., Zhu, C., Zhang, Y., Zhang, C., Yao, W. Tags: Research Article Source Type: research