Interleukin-1{beta} overproduction is a common cause for neuropathic pain, memory deficit, and depression following peripheral nerve injury in rodents

Conclusions Neuropathic pain was not necessary for the development of cognitive and emotional disorders, while the overproduction of IL-1β in the injured sciatic nerve following peripheral nerve injury may be a common mechanism underlying the generation of neuropathic pain, memory deficit, and depression.

http://mpx.sagepub.com/cgi/content/abstract/12/0/1744806916646784?rss=1

Source: Molecular Pain - May 11, 2016 Category: Molecular Biology Authors: Gui, W.-S., Wei, X., Mai, C.-L., Murugan, M., Wu, L.-J., Xin, W.-J., Zhou, L.-J., Liu, X.-G. Tags: Research Article Source Type: research