Rho/ROCK acts downstream of lysophosphatidic acid receptor 1 in modulating P2X3 receptor-mediated bone cancer pain in rats

Conclusions Lysophosphatidic acid and its receptor LPAR1, acting through the Rho-ROCK pathway, regulate P2X3 receptor in the development of both mechanical and spontaneous pain in bone cancer.

http://mpx.sagepub.com/cgi/content/abstract/12/0/1744806916644929?rss=1

Source: Molecular Pain - April 17, 2016 Category: Molecular Biology Authors: Wu, J.-x., Yuan, X.-m., Wang, Q., Wei, W., Xu, M.-y. Tags: Research Article Source Type: research