ERK-GluR1 phosphorylation in trigeminal spinal subnucleus caudalis neurons is involved in pain associated with dry tongue

Conclusions
These findings suggest that the pERK-pGluR1 cascade is involved in central sensitization of trigeminal spinal subnucleus caudalis nociceptive neurons, thus resulting in tongue mechanical hyperalgesia associated with tongue drying.

Source: Molecular Pain - April 25, 2016 Category: Molecular Biology Authors: Nakaya, Y., Tsuboi, Y., Okada-Ogawa, A., Shinoda, M., Kubo, A., Chen, J. Y., Noma, N., Batbold, D., Imamura, Y., Sessle, B. J., Iwata, K. Tags: Research Article Source Type: research