Regulation of transient receptor potential vanilloid 1 expression in trigeminal ganglion neurons via methyl-CpG binding protein 2 signaling contributes tongue heat sensitivity and inflammatory hyperalgesia in mice

Conclusions These findings indicate that tongue heat sensitivity and hypersensitivity are dependent on the expression of transient receptor potential vanilloid 1 which is regulated via MeCP2 signaling in trigeminal ganglion neurons innervating the tongue.

http://mpx.sagepub.com/cgi/content/abstract/12/0/1744806916633206?rss=1

Source: Molecular Pain - March 7, 2016 Category: Molecular Biology Authors: Suzuki, A., Shinoda, M., Honda, K., Shirakawa, T., Iwata, K. Tags: Research Article Source Type: research