Reductions in expression of growth regulating genes in skeletal muscle with age in wild type and myostatin null mice

Conclusions:
Overall, these data suggest the downregulation of these growth-regulating genes with age might play a role in the coordinated cessation of muscle growth similar to organ growth but likely have a limited role in the differences between sexes or genotypes.

Source: BMC Physiology - Latest articles - March 28, 2014 Category: Physiology Authors: Jennifer JonesKellie KroscherAnna Dilger Source Type: research