Cognitive performance, fatigue and event-related potentials in patients with clinically isolated syndrome.

Multiple sclerosis (MS) is a chronic disease of the central nervous system with a background associated with immune-mediated demyelinating processes accompanied by axonal loss. Multifocal and diffuse damage to the brain results in a diversity of symptoms and signs of neurological deficit. Among these, cognitive impairment and fatigue have already been recognized and investigated because they substantially affect patients' social and vocational functioning [1–4]. Impaired cognitive performance is reported in 30-70% of MS patients and is still supposed to be underestimated [1,2].

Source: Clinical Neurology and Neurosurgery - July 13, 2016 Category: Neurosurgery Authors: Anna Pokryszko-Dragan, Edyta Dziadkowiak, Mieszko Zagrajek, Krzysztof Slotwinski, Ewa Gruszka, Malgorzata Bilinska, Ryszard Podemski Source Type: research