Augmentation of the Inotropic Effects of Dopamine Following Linezolid Administration in an Infant

We present a 3-month-old infant who was being treated with dopamine to maintain mean arterial pressure during mechanical ventilation following viral-induced respiratory failure. Hypertension and tachycardia developed during the administration of linezolid on two separate occasions. The physiology of catecholamine metabolism is reviewed including the role of the monoamine oxidase system. The potential interaction between linezolid and vasoactive agents such as dopamine is discussed.

Source: Journal of Intensive Care Medicine - July 11, 2016 Category: Intensive Care Authors: Lovett, M. E., Estrada, M., Sargel, C., Tobias, J. D. Tags: Case Report Source Type: research