Comparison of pulmonary arterial wall properties between a congenital heart disease patient and a normal subject using in vivo pressure–diameter measurements: A feasibility study

Patients with congenital heart disease (CHD) requiring pulmonary valve and right ventricular intervention often suffer from residual lesions including pulmonary regurgitation or pulmonary artery (PA) obstruction after the placement of a patch or artificial conduit during surgery. These residual lesions can result in significant changes in the structure and function of the right ventricle (RV) and PA. Characterization of the material properties such as stress, strain, and compliance of the PA provides a quantitative assessment of RV–PA dysfunction and may aid in the longitudinal assessment of CHD patients.
Source: Progress in Pediatric Cardiology - Category: Cardiology Authors: Source Type: research