Heart transplantation in adults for Fontan failure

Since the original description of atriopulmonary connection for palliation of univentricular circulations in 1971 by Fontan and Baudet [1], thousands of patients have undergone variations of Fontan palliation for single ventricle physiology. While Fontan surgery offers effective palliation, by 20years after Fontan palliation approximately 30% of patients have experienced death or need for transplant [2–4]. Management of Fontan failure can be challenging due to varying etiologies, often involving multiple organ systems.
Source: Progress in Pediatric Cardiology - Category: Cardiology Authors: Tags: Review Source Type: research