Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in {beta}-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption

In conclusion, both 1,25(OH)2D3 and hepcidin could be used to alleviate the β-thalassemia-associated impairment of calcium absorption. Therefore, our study has shed light on the development of a treatment strategy to rescue calcium dysregulation in β-thalassemia.

Source: AJP: Endocrinology and Metabolism - July 4, 2016 Category: Endocrinology Authors: Kraidith, K., Svasti, S., Teerapornpuntakit, J., Vadolas, J., Chaimana, R., Lapmanee, S., Suntornsaratoon, P., Krishnamra, N., Fucharoen, S., Charoenphandhu, N. Tags: Articles Source Type: research