The PARP inhibitor PJ-34 sensitizes cells to UVA-induced phototoxicity by a PARP independent mechanism

In conclusion, PJ-34 is a photosensitizer and PJ–34+UVA causes DNA damage and caspase-mediated cell death independently of PARP-1 inhibition. Graphical abstract
Source: Mutation Research Fundamental and Molecular Mechanisms of Mutagenesis - Category: Cytology Source Type: research