Acute and crucial requirement for MeCP2 function upon transition from early to late adult stages of brain maturation

This study reveals a new postnatal developmental stage, which coincides with full-brain maturation, where the structure/function of the brain is extremely sensitive to levels of MeCP2 and loss of MeCP2 leads to precipitous collapse of the neuronal networks and incompatibility with life within days.

Source: Human Molecular Genetics - July 4, 2016 Category: Genetics & Stem Cells Authors: Du, F., Nguyen, M. V. C., Karten, A., Felice, C. A., Mandel, G., Ballas, N. Tags: ARTICLES Source Type: research