Optimization and Characterization of Lipase Catalysed Synthesis Of Xylose Caproate Ester in Organic Solvents

Publication date: Available online 23 June 2016 Source:Journal of Molecular Catalysis B: Enzymatic Author(s): Emilia Abdulmalek, Noor Fazrieyana Hamidon, Mohd Basyaruddin Abdul Rahman The lipase catalysed synthesis of xylose caproate ester was performed by condensation of xylose, an aldopentose and caproic acid in organic solvents. A dual-solvent system containing DMSO and acetone (1:10v/v) was used to determine the optimal conditions for the reaction. Different reaction parameters (solvent system, reaction time, substrate molar ratio and the amount of enzyme loaded) were studied. The highest conversion rate (64%) was obtained within 24hours with the optimal conditions of 16% (w/v) Novozym 435 and a molar ratio of xylose to caproic acid of 1:4. Graphical abstract

Source: Journal of Molecular Catalysis B: Enzymatic - July 3, 2016 Category: Biochemistry Source Type: research