Cellular zinc is required for intestinal epithelial barrier maintenance via the regulation of claudin-3 and occludin expression

This study shows that intracellular zinc has an essential role in the maintenance of the intestinal epithelial TJ barrier through regulation of occludin proteolysis and claudin-3 transcription.

Source: AJP: Gastrointestinal and Liver Physiology - June 30, 2016 Category: Gastroenterology Authors: Miyoshi, Y., Tanabe, S., Suzuki, T. Tags: EPITHELIAL BIOLOGY AND SECRETION Source Type: research