Effects of Memantine on Aminoglycoside-Induced Apoptosis of Spiral Ganglion Cells in Guinea Pigs

Conclusion Memantine attenuated the gentamicin-induced apoptosis of SGCs in guinea pigs. Moreover, memantine may affect Fas-FasL signaling in the receptor-mediated apoptotic pathway and caspase activation involved in the receptor-mediated and mitochondrial apoptotic pathways.

http://oto.sagepub.com/cgi/content/abstract/155/1/147?rss=1

Source: Otolaryngology - Head and Neck Surgery - June 30, 2016 Category: ENT & OMF Authors: Kim, B. Y., Bae, W. Y., Hur, D. Y., Kim, J.-R., Koh, T. K., Lee, T. H., Park, G. B. Tags: Otology and Neurotology Source Type: research