Ciprofloxacin Decreases Collagen in Mouse Tympanic Membrane Fibroblasts

Conclusions Treatment of tympanic membrane fibroblasts with 0.3% ciprofloxacin, as found in eardrops, reduces fibroblast viability and collagen and α-tubulin protein levels. These findings could explain tympanic membrane healing problems associated with quinolone eardrops.

http://oto.sagepub.com/cgi/content/abstract/155/1/127?rss=1

Source: Otolaryngology - Head and Neck Surgery - June 30, 2016 Category: ENT & OMF Authors: Orobello, N. C., Dirain, C. O., Schultz, G., Milne-Davies, B. A., Ng, M. R. A., Antonelli, P. J. Tags: Otology and Neurotology Source Type: research