AP2-NR4A3 transgenic mice display reduced serum epinephrine because of increased catecholamine catabolism in adipose tissue

In conclusion, overexpression of NR4A3 in adipocytes produces a complex phenotype characterized by impaired glucose metabolism and low serum catecholamines due to enhanced degradation by adipose tissue.

Source: AJP: Endocrinology and Metabolism - June 30, 2016 Category: Endocrinology Authors: Walton, R. G., Zhu, X., Tian, L., Heywood, E. B., Liu, J., Hill, H. S., Liu, J., Bruemmer, D., Yang, Q., Fu, Y., Garvey, W. T. Tags: Call for Papers Source Type: research