The Leishmaniasis East Africa Platform (LEAP): strengthening clinical trial capacity in resource-limited countries to deliver new treatments for visceral leishmaniasis

Visceral leishmaniasis is a neglected tropical disease endemic in East Africa where improved patient-adapted treatments are needed. The Leishmaniasis East Africa Platform (LEAP) was created in 2003 to strengthen clinical research capacity, serve as a base for training, and evaluate and facilitate implementation of new treatments. Major infrastructure upgrades and personnel training have been carried out. A short course of Sodium Stibogluconate and Paramomycin (SSG&PM) was evaluated and is now first-line treatment in the region; alternative treatments have also been assessed. LEAP can serve as a successful model of collaboration between different partners and countries when conducting clinical research in endemic countries to international standards.

Source: Transactions of the Royal Society of Tropical Medicine and Hygiene - June 28, 2016 Category: Tropical Medicine Authors: Wasunna, M., Musa, A., Hailu, A., Khalil, E. A. G., Olobo, J., Juma, R., Wells, S., Alvar, J., Balasegaram, M. Tags: Commentary Source Type: research