Inflammasomes: mechanism of assembly, regulation and signalling
Nature Reviews Immunology 16, 407 (2016).
doi:10.1038/nri.2016.58
Authors: Petr Broz & Vishva M. Dixit
Inflammasomes are multiprotein signalling platforms that control the inflammatory response and coordinate antimicrobial host defences. They are assembled by pattern-recognition receptors following the detection of pathogenic microorganisms and danger signals in the cytosol of host cells, and they activate inflammatory caspases to produce cytokines and
Source: Nature Reviews Immunology - Category: Allergy & Immunology Authors: Petr BrozVishva M. Dixit Tags: Review Source Type: research
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