Using Contour Plots to Assess the Sensitivity of Clinical Trial Design Assumptions

Conclusions: Contour plots are a useful tool for the study team in designing clinical trials, and they can be included in study documents to better communicate the rationale for sample size for clinicians and regulators. Contour plots provide greater transparency as to the uncertainty of the currently available information, and can be useful in deciding whether to consider adaptive designs.
Source: Therapeutic Innovation and Regulatory Science - Category: Drugs & Pharmacology Authors: Tags: Statistics Source Type: research