Stem Cell Surface Marker Expression Defines Late Stages of Reprogramming to Pluripotency in Human Fibroblasts

This report describes tools to study the late stages of cellular reprogramming. The findings enable a more precise approach to dissecting the final phases of conversion to pluripotency, a process that is particularly poorly defined. The results of this study also provide a simple new method for the selection of fully reprogrammed cells, which could enhance the efficiency of derivation of cell lines for research and therapy.

Source: Stem Cells Translational Medicine - June 26, 2016 Category: Stem Cells Authors: Pomeroy, J. E., Hough, S. R., Davidson, K. C., Quaas, A. M., Rees, J. A., Pera, M. F. Tags: Pluripotent Stem Cells, Pluripotent Stem Cells Source Type: research