Arsenite and Cadmium Activate MAPK/ERK via Membrane Estrogen Receptors and G-Protein Coupled Estrogen Receptor Signaling in Human Lung Adenocarcinoma Cells

This study supports the involvement of membrane ER and GPER signaling in mediating cellular responses to environmentally relevant nM concentrations of CdCl2 and NaAsO2 in lung adenocarcinoma cells.

Source: Toxicological Sciences - June 26, 2016 Category: Toxicology Authors: Huff, M. O., Todd, S. L., Smith, A. L., Elpers, J. T., Smith, A. P., Murphy, R. D., Bleser-Shartzer, A. S., Hoerter, J. E., Radde, B. N., Klinge, C. M. Tags: MAPK/ERK Activation by Arsenite and Cadmium Source Type: research