Resveratrol inhibits glucose‐induced migration of vascular smooth muscle cells mediated by focal adhesion kinase

ConclusionThe antimigratory effects of resveratrol by reduced MMP expression through the inhibition of Rac1, p‐FAK, and lamellipodia formation and the activation of p‐AKT and p‐ERK1/2 suggest that resveratrol is a potential compound for the treatment of vascular diseases via the regulation of VSMC migration.

Source: Molecular Nutrition - March 1, 2014 Category: Nutrition Authors: Yi‐Chiao Lin, Li‐Hsuen Chen, T. Varadharajan, May‐Jywan Tsai, Yi‐Chen Chia, Ta‐Chun Yuan, Ping‐Jyun Sung, Ching‐Feng Weng Tags: Research Article Source Type: research