Systemic complement activation and complement gene analysis in enterohaemorrhagic Escherichia coli-associated paediatric haemolytic uraemic syndrome

Conclusions Complement activation at the acute phase of EHEC-HUS, indicated by increased levels of sC5b-9, predicts a poor outcome. Complement alterations appear to be more frequent in patients with EHEC-HUS than previously thought and are suspected to have a role in the severity of the disease.

http://ndt.oxfordjournals.org/cgi/content/short/31/7/1114?rss=1

Source: Nephrology Dialysis Transplantation - June 21, 2016 Category: Urology & Nephrology Authors: Ahlenstiel-Grunow, T., Hachmeister, S., Bange, F. C., Wehling, C., Kirschfink, M., Bergmann, C., Pape, L. Tags: Acute Kidney Injury Source Type: research