Cognitive effects of second‐generation antidepressants in the elderly

It is not uncommon for patients with depression to exhibit cognitive deficits, such as impaired attention, information processing, and memory.1 Some studies suggest that antidepressants can improve neurocognitive function via their beneficial effects on depressive symptomatology and neurophysiological changes in the brain. However, there is conflicting evidence, which could be related to the different receptor binding properties and sites of action of individual antidepressants. Currently, there is limited information regarding comparative cognitive effects among various antidepressants in elderly patients with depression.

Source: The Brown University Psychopharmacology Update - June 21, 2016 Category: Psychiatry Authors: Y. W. Francis Lam Tags: Drug ‐Drug Interactions Source Type: research