DNA damage response: Cell thriving despite DNA damage

Nature Reviews Molecular Cell Biology 17, 396 (2016). doi:10.1038/nrm.2016.86 Author: Paulina Strzyz DNA damage response (DDR) pathways prevent genomic instability by inducing cell-cycle arrest, DNA repair or apoptosis following DNA damage, and are known to be inactivated in polyploid cells as well as in many cancers. Bretscher and Fox used the developing fly papillar cells — a
Source: Nature Reviews Molecular Cell Biology - Category: Cytology Authors: Tags: Research Highlight Source Type: research