Development of a minipig model for lung injury induced by a single high-dose radiation exposure and evaluation with thoracic computed tomography

In conclusion, the minipig model can provide useful clinical data regarding RILI caused by the adverse effects of high-dose radiotherapy. Peribronchial opacification, interlobular septal thickening, and lung volume loss are three quantifiable CT parameters that can be used as a simple method for monitoring the progression of RILI.

Source: Journal of Radiation Research - June 20, 2016 Category: Physics Authors: Lee, J.-G., Park, S., Bae, C.-H., Jang, W.-S., Lee, S.-J., Lee, D. N., Myung, J. K., Kim, C. H., Jin, Y.-W., Lee, S.-S., Shim, S. Tags: Regular paper Source Type: research