Complex transfusion issues in pediatric hematopoietic stem cell transplantation

Advances in the fields of pediatric transfusion medicine and hematopoietic stem cell transplant have resulted in improved outcomes but also present new questions for research. The diagnostic capabilities involved in transfusion medicine have improved in recent times now including methods for determination of RBC minor antigen, detection of anti-HLA antibodies, and non-invasive iron quantification. At the same time transplants are being performed for more indications including non-malignant disease and with less intense conditioning regimens that allow some recipient blood cells to persist after transplant.
Source: Transfusion Medicine Reviews - Category: Hematology Authors: Source Type: research