Histological chorioamnionitis shapes the neonatal transcriptomic immune response

Histologic chorioamnionitis (HCA) is commonly associated with preterm birth and deleterious post-natal outcomes including sepsis and necrotizing enterocolitis. Transcriptomic analysis has been used to uncover gene signatures that permit diagnosis and prognostication, show new therapeutic targets, and reveal mechanisms that underlie differential outcomes with other complex disease states in neonates such as sepsis.
Source: Early Human Development - Category: Perinatology & Neonatology Authors: Source Type: research