Changes in CREB and deltaFosB are associated with the behavioural sensitization induced by methylenedioxypyrovalerone

This study constitutes the first evidence that an exposure to a low dose of MDPV during adolescence induces behavioural sensitization and provides a neurobiological basis for a relationship between MDPV and cocaine. We hypothesize that, similar to cocaine, both CREB and deltaFosB play a role in the induction of this behavioural sensitization.

Source: Journal of Psychopharmacology - June 15, 2016 Category: Psychiatry Authors: Buenrostro-Jauregui, M., Ciudad-Roberts, A., Moreno, J., Munoz-Villegas, P., Lopez-Arnau, R., Pubill, D., Escubedo, E., Camarasa, J. Tags: Short Report Source Type: research