Donepezil modulates the endogenous immune response: implications for Alzheimer's disease

ConclusionsDonepezil might modulate a T helper 2 bias via α7nAChR leading to increased expression of NAb. Further studies on the role of the modulation of the immune response against Aβ may pave the way to innovative therapeutic strategies for AD. Copyright © 2016 John Wiley & Sons, Ltd.

Source: Human Psychopharmacology: Clinical and Experimental - June 12, 2016 Category: Psychiatry Authors: Elisa Conti, Lucio Tremolizzo, Marta Elena Santarone, Marco Tironi, Isabella Radice, Chiara Paola Zoia, Angelo Aliprandi, Andrea Salmaggi, Roberto Dominici, Marco Casati, Ildebrando Appollonio, Carlo Ferrarese Tags: Research Article Source Type: research