Optical coherence tomography indicates disease activity prior to clinical onset of central nervous system demyelination

Conclusion: Patients with radiologically and clinically isolated syndromes behave similarly concerning paraclinical disease activity in cerebral magnetic resonance imaging. In both conditions, reduction of retinal nerve fibre layer and increased inner nuclear layer and outer nuclear layer volumes predict disease activity and are associated with progression into multiple sclerosis.
Source: Multiple Sclerosis - Category: Neurology Authors: Tags: Original Research Papers Source Type: research