Revisiting the reported signal of acute pancreatitis with rasburicase: an object lesson in pharmacovigilance

Discussion: Our exercise stimulated interesting discussions of key points in signal detection and evaluation, including causality assessment, signal detection algorithm performance, pharmacovigilance terminology, duplicate reporting, mechanisms for communicating signals, the structure of the FAERs database, and recent results from a major international pharmacovigilance research initiative.
Source: Therapeutic Advances in Drug Safety - Category: Drugs & Pharmacology Authors: Tags: Original Research Source Type: research