Transcriptional modulation of SLC26A3 (DRA) by sphingosine-1-phosphate

In conclusion, transcriptional modulation of DRA expression and function in response to S1P through a PI3/Akt pathway represents a novel role of S1P as a potential proabsorptive agent.

http://ajpgi.physiology.org/cgi/content/abstract/310/11/G1028?rss=1

Source: AJP: Gastrointestinal and Liver Physiology - May 31, 2016 Category: Gastroenterology Authors: Anbazhagan, A. N., Priyamvada, S., Alakkam, A., Kumar, A., Borthakur, A., Saksena, S., Gill, R. K., Alrefai, W. A., Dudeja, P. K. Tags: EPITHELIAL BIOLOGY AND SECRETION Source Type: research