Implantation of Autologous Cartilage Chips Improves Cartilage Repair Tissue Quality in Osteochondral Defects: A Study in Göttingen Minipigs

Conclusion: The presence of cartilage chips in an osteochondral defect facilitated the formation of fibrocartilage as opposed to fibrous tissue at both 6 and 12 months posttreatment. The implanted chips were present in the defect and viable after 12 months. Clinical Relevance: This study substantiates the chondrogenic role of cartilage chips in osteochondral defects.
Source: The American Journal of Sports Medicine - Category: Sports Medicine Authors: Tags: Biology of cartilage, Tissue engineering, Knee, articular cartilage, Articular cartilage resurfacing Biology and Translational Research Source Type: research