Inhibition of Inflammation-Associated Olfactory Loss by Etanercept in an Inducible Olfactory Inflammation Mouse Model

Conclusion Concomitant administration of etanercept in IOI mice results in interruption of TNF-α-induced olfactory loss and induction of neuroepithelial regeneration. This demonstrates that etanercept has potential utility as a tool for elucidating the role of TNF-α in other olfactory inflammation models.

http://oto.sagepub.com/cgi/content/abstract/154/6/1149?rss=1

Source: Otolaryngology - Head and Neck Surgery - May 31, 2016 Category: ENT & OMF Authors: Jung, Y. G., Lane, A. P. Tags: Sinonasal Disorders Source Type: research