Adjuvant Radiation Therapy and Chemotherapy in Merkel Cell Carcinoma: Survival Analyses of 6908 Cases From the National Cancer Data Base

Conclusions: In this study of the largest MCC cohort reported to date, adjuvant RT was associated with improved OS in stages I-II MCC. Neither adjuvant RT nor chemotherapy was associated with improved OS in stage III MCC. These results, with the limitations of retrospective analyses, are consistent with earlier studies suggesting benefit with adjuvant RT but do not support the routine use of adjuvant chemotherapy in MCC.

Source: JNCI - May 30, 2016 Category: Cancer & Oncology Authors: Bhatia, S., Storer, B. E., Iyer, J. G., Moshiri, A., Parvathaneni, U., Byrd, D., Sober, A. J., Sondak, V. K., Gershenwald, J. E., Nghiem, P. Tags: Article Source Type: research