A Study of Human Killer Cell Immunoglobulin-Like Receptor and Multidrug Resistance Gene Polymorphisms in Children With Immune Thrombocytopenia

Conclusion:
The frequency of MDR1 polymorphisms was not associated with susceptibility to the development and clinical progression of the disease. However, KIR2 gene polymorphisms were independently associated with childhood ITP in Egyptian patients with highest prevalence among (KIRDL2–/KIRDS2–) genotypes.

Source: Clinical and Applied Thrombosis/Hemostasis - May 28, 2016 Category: Hematology Authors: El-beblawy, N. M. S., Elbarbary, N. S., Kamal, T. M., Mahmoud, P. M. Tags: Original Articles Source Type: research