Evidence-Based Development and Rationale for Once-Daily Rivaroxaban Dosing Regimens Across Multiple Indications

Conclusion:
The evidence for each dosing regimen demonstrates that although pharmacology studies are of paramount importance, dose regimens must be subjected to careful empirical validation. Once-daily dosing was shown to be clinically appropriate for most rivaroxaban indications. Furthermore, a "one size fits all" approach to dosing frequency is unlikely to result in a regimen that yields optimal patient outcomes across different indications.

Source: Clinical and Applied Thrombosis/Hemostasis - May 28, 2016 Category: Hematology Authors: Kubitza, D., Berkowitz, S. D., Misselwitz, F. Tags: Reviews Source Type: research