Treatment with Glucocorticoids or Calcineurin Inhibitors in Primary FSGS

In the 458 patients were studied, the use of calcineurin inhibitors and/or glucocorticoids as part of the early immunosuppressive regimen in primary FSGS was associated with improved renal outcome.  However, the superiority of calcineurin inhibitors over glucocorticoids alone remains unproven.   : Fixed- or Controlled-Dose Mycophenolate Mofetil with Standard- or Reduced-dose Calcineurin Inhibitors: The Opticept Trial A Phase III Study of Belatacept-based Immunosuppression Regimens versus Cyclosporine in Renal Transplant Recipients (BENEFIT Study) The ORION Study: Comparison of Two Sirolimus-Based Regimens versus Tacrolimus and Mycophenolate Mofetil in Renal Allograft Recipients
Source: Nephrology Now - Category: Urology & Nephrology Authors: Tags: Clinical Nephrology Glomerulonephritis Source Type: research