Mechanisms of human lymphoid chromosomal translocations

Nature Reviews Cancer 16, 387 (2016). doi:10.1038/nrc.2016.40 Author: Michael R. Lieber Analysis of chromosomal translocation sequence locations in human lymphomas has provided valuable clues about the mechanism of the translocations and when they occur. Biochemical analyses on the mechanisms of DNA breakage and rejoining permit formulation of detailed models of the human chromosomal translocation process in
Source: Nature Reviews Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research