Angiopoietin-2 expression in patients with an acute exacerbation of idiopathic interstitial pneumonias

We hypothesized that increased pulmonary vascular permeability may play a role in the pathogenesis of an acute exacerbation of the idiopathic interstitial pneumonias (AE-IIPs). Angiopoietin-2 (Ang-2) promotes endothelial activation, destabilization, and inflammation. The purpose of this study was to examine whether Ang-2 expression was associated with the pathogenesis of AE-IIPs.

Source: Respiratory Medicine CME - May 23, 2016 Category: Respiratory Medicine Authors: Masaru Ando, Eishi Miyazaki, Tetsutaro Abe, Chihiro Ehara, Akihiro Goto, Taiki Masuda, Suehiro Nishio, Hideaki Fujisaki, Mari Yamasue, Toshihiro Ishii, Yutaka Mukai, Takeo Ito, Shin-ich Nureki, Toshihide Kumamoto, Junichi Kadota Source Type: research