Plasma bupivacaine concentrations following orbital injections in cats

Conclusions and clinical relevanceIn healthy cats, at doses up to 2 mg kg−1, bupivacaine peak plasma concentrations were approximately half that reported to cause arrhythmias or convulsive electroencephalogram (EEG) activity in cats, and about one‐sixth of that required to produce hypotension.

Source: Veterinary Anaesthesia and Analgesia - April 30, 2016 Category: Veterinary Research Authors: Yael Shilo‐Benjamini, Bruno H Pypendop, Georgina Newbold, Peter J Pascoe Tags: Short Communication Source Type: research