Can supplementation of phytoestrogens/insoluble fibers help the management of duodenal polyps in familial adenomatous polyposis?

In conclusion, ADI proved to be safe and effective, and its long-term effects on FAP patients need further investigation. Judging from the results we observed on COX-2 and miR-101 expression, the short-term effects of ADI treatment could be comparable with those obtained using COX-2 inhibitors, with the advantage of being much more tolerable in chronic therapies and void of adverse events.

Source: Carcinogenesis - May 22, 2016 Category: Cancer & Oncology Authors: Calabrese, C., Rizzello, F., Gionchetti, P., Calafiore, A., Pagano, N., De Fazio, L., Valerii, M. C., Cavazza, E., Strillacci, A., Comelli, M. C., Poggioli, G., Campieri, M., Spisni, E. Tags: Original Manuscript Source Type: research