Effect of genotype on the severity and volume progression of polycystic liver disease in autosomal dominant polycystic kidney disease

Conclusions In contrast to the renal phenotype, the ADPKD genotype was not associated with the severity or growth rate of PLD in ADKPD patients. This finding, along with gender influence, indicates that modifiers beyond the disease gene significantly influence the liver phenotype.

http://ndt.oxfordjournals.org/cgi/content/short/31/6/952?rss=1

Source: Nephrology Dialysis Transplantation - May 22, 2016 Category: Urology & Nephrology Authors: Chebib, F. T., Jung, Y., Heyer, C. M., Irazabal, M. V., Hogan, M. C., Harris, P. C., Torres, V. E., El-Zoghby, Z. M. Tags: Chronic Kidney Disease Source Type: research