Determination of Insecticidal Effect (LC50 and LC90) of Organic Fatty Acids Mixture (C8910+Silicone) Against Aedes aegypti and Aedes albopictus (Diptera: Culicidae)

Emerging and re-emerging vector-borne diseases such as chikungunya and dengue and associated Aedes vectors are expanding their historical ranges; thus, there is a need for the development of novel insecticides for use in vector control programs. The mosquito toxicity of a novel insecticide and repellent consisting of medium-chain carbon fatty acids (C8910) was examined. Determination of LC50 and LC90 was made against colony-reared Aedes aegypti (L.) and Aedes albopictus (Skuse) using probit analysis on mortality data generated by Centers for Disease Control and Prevention bottle bioassays. Six different concentrations of C8910 + silicone oil yielded an LC50 of 160.3 µg a.i/bottle (147.6–182.7) and LC90 of 282.8 (233.2–394.2) in Ae. aegypti; five concentrations yielded an LC50 of 125.4 (116.1–137.6) and LC90 of 192.5 (165.0–278.9) in Ae. albopictus. Further development of C8910 and similar compounds could provide vector control specialists novel insecticides for controlling insect disease vectors.

Source: Journal of Medical Entomology - May 19, 2016 Category: Biology Authors: Dunford, J. C., Falconer, A., Leite, L. N., Wirtz, R. A., Brogdon, W. G. Tags: Short Communication Source Type: research