Acute interstitial nephritis induced by Solanum nigrum

Publication date: Available online 18 May 2016 Source:Kidney Research and Clinical Practice Author(s): Sung Sik Oh, Myung Woo Choi, Jong Hwa Lee, Hyun Ju Yang, Yeong Jin Choi, Kwang Young Lee, In O. Sun Acute interstitial nephritis (AIN) is an important cause of reversible acute kidney injury and is pathologically characterized by inflammatory infiltrate in the renal interstitium. Solanum nigrum (S. nigrum) is a medicinal plant member of the Solanaceae family. While S. nigrum has been traditionally used to treat various ailments such as pain, inflammation, and fever, it has also been reported to have a toxic effect, resulting in anticholinergic symptoms. However, there have been no reports of AIN caused by S. nigrum. Here, we report the first case of biopsy-confirmed AIN following ingestion of S. nigrum. The patient was successfully treated using corticosteroid therapy.
Source: Kidney Research and Clinical Practice - Category: Urology & Nephrology Source Type: research